| Gene Information | |
|---|---|
| Gene Name | UCHL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 230 |
| Protein Names | Ubiquitin carboxyl-terminal hydrolase isozyme L3 (UCH-L3) (EC 3.4.19.12) (Ubiquitin thioesterase L3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000118939 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P15374 |
| Gene Card | UCHL3 |
| Uniprot ID | P15374 |
| Pfam | PF01088 |
| In ASD | yes |
| Allosteric Prediction | no (-0.003872948) |
| Ortholog in Animals | Alpaca_ UCHL3 ( ortholog_one2one ) Dog_ UCHL3 ( ortholog_one2one ) Macaque_ UCHL3 ( ortholog_one2one ) Mouse_ Uchl3 ( ortholog_one2many ) Mouse_ Uchl4 ( ortholog_one2many ) Pig_ UCHL3 ( ortholog_one2one ) Rat_ Uchl3 ( ortholog_one2many ) Rabbit_ UCHL3 ( ortholog_one2one ) |
| Ohnologs | UCHL1 |
| Paralogs | UCHL1, BAP1, UCHL5 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart, skeletal muscle, and testis. {ECO:0000269|PubMed:9790970}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1UCH (X-ray 1.80A ) 1XD3 (X-ray 1.45A ) 6ISU (X-ray 1.87A ) 6QML (X-ray 2.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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