| Gene Information | |
|---|---|
| Gene Name | PPP2R5D |
| Organism | Homo sapiens (Human) |
| Gene Length | 602 |
| Protein Names | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000112640 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14738 |
| Gene Card | PPP2R5D |
| Uniprot ID | Q14738 |
| Pfam | PF01603 |
| In ASD | no |
| Allosteric Prediction | yes (1.008644059) |
| Ortholog in Animals | Alpaca_ PPP2R5D ( ortholog_one2one ) Dog_ PPP2R5D ( ortholog_one2one ) GuineaPig_ PPP2R5D ( ortholog_one2one ) Macaque_ PPP2R5D ( ortholog_one2one ) Mouse_ Ppp2r5d ( ortholog_one2one ) Pig_ PPP2R5D ( ortholog_one2one ) Rat_ Ppp2r5d ( ortholog_one2one ) Rabbit_ PPP2R5D ( ortholog_one2one ) |
| Ohnologs | PPP2R5C |
| Paralogs | PPP2R5C, PPP2R5A, PPP2R5B, PPP2R5E |
| Tissue | NA |
| Tissue Specificity | Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.036364(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs757369209 rs863225082 rs863225079 rs876657383 rs869320691 |
| Subcellular location [CC] | Cytoplasm. Nucleus. Note=Nuclear in interphase, nuclear during mitosis. |
| Mouse PG classification | LPG |
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