Gene Information
Gene NamePPP2R5B
OrganismHomo sapiens (Human)
Gene Length497
Protein NamesSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (PP2A B subunit isoform B'-beta) (PP2A B subunit isoform B56-beta) (PP2A B subunit isoform PR61-beta) (PP2A B subunit isoform R5-beta)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000068971 )
Evolutionary StageEukaryota
AlphaFoldDBQ15173
Gene CardPPP2R5B
Uniprot IDQ15173
PfamPF01603
In ASDno
Allosteric Predictionyes (0.765042948)
Ortholog in AnimalsAlpaca_ PPP2R5B ( ortholog_one2one )
Dog_ PPP2R5B ( ortholog_one2one )
GuineaPig_ PPP2R5B ( ortholog_one2one )
Macaque_ PPP2R5B ( ortholog_one2one )
Mouse_ Ppp2r5b ( ortholog_one2one )
Pig_ PPP2R5B ( ortholog_one2one )
Rat_ Ppp2r5b ( ortholog_one2one )
Rabbit_ PPP2R5B ( ortholog_one2one )
OhnologsPPP2R5E, PPP2R5A
ParalogsPPP2R5A, PPP2R5E, PPP2R5D, PPP2R5C
TissueNA
Tissue SpecificityHighest expression in brain.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.005276(Rat);0.060000(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:8703017}.
Mouse PG classificationNA
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