| Gene Information | |
|---|---|
| Gene Name | PRMT6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 375 |
| Protein Names | Protein arginine N-methyltransferase 6 (EC 2.1.1.319) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6) (Histone-arginine N-methyltransferase PRMT6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000198890 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96LA8 |
| Gene Card | PRMT6 |
| Uniprot ID | Q96LA8 |
| Pfam | PF13649 |
| In ASD | yes |
| Allosteric Prediction | yes (0.456293648) |
| Ortholog in Animals | Alpaca_ PRMT6 ( ortholog_one2one ) Dog_ PRMT6 ( ortholog_one2one ) GuineaPig_ PRMT6 ( ortholog_one2one ) Macaque_ PRMT6 ( ortholog_one2one ) Mouse_ Prmt6 ( ortholog_one2one ) Pig_ PRMT6 ( ortholog_one2one ) Rat_ Prmt6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PRMT2, PRMT7, PRMT9, PRMT1, CARM1, PRMT3, PRMT8 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in kidney and testis. {ECO:0000269|PubMed:11724789}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4HC4 (X-ray 1.97A ) 4QPP (X-ray 2.52A ) 4QQK (X-ray 1.88A ) 4Y2H (X-ray 2.37A ) 4Y30 (X-ray 2.10A ) 5E8R (X-ray 2.55A ) 5EGS (X-ray 2.15A ) 5HZM (X-ray 2.02A ) 5WCF (X-ray 1.98A ) 6P7I (X-ray 2.00A ) 6W6D (X-ray 1.91A ) 6WAD (X-ray 2.45A ) 7NR4 (X-ray 2.03A ) |
| DBSNP | rs2232016 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11724789}. |
| Mouse PG classification | NA |
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