| Gene Information | |
|---|---|
| Gene Name | PPP1R3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 285 |
| Protein Names | Protein phosphatase 1 regulatory subunit 3B (Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL) (Protein phosphatase 1 regulatory subunit 4) (PP1 subunit R4) (Protein phosphatase 1 subunit GL) (PTG) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000173281 ) 3 ( ENSG00000285343 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q86XI6 |
| Gene Card | PPP1R3B |
| Uniprot ID | Q86XI6 |
| Pfam | PF03370 |
| In ASD | no |
| Allosteric Prediction | no (-0.202822684) |
| Ortholog in Animals | Alpaca_ PPP1R3B ( ortholog_one2one ) Dog_ PPP1R3B ( ortholog_one2one ) GuineaPig_ PPP1R3B ( ortholog_one2one ) Macaque_ PPP1R3B ( ortholog_one2one ) Mouse_ Ppp1r3b ( ortholog_one2one ) Pig_ PPP1R3B ( ortholog_one2one ) Rat_ Ppp1r3b ( ortholog_one2one ) Rabbit_ PPP1R3B ( ortholog_one2one ) |
| Ohnologs | PPP1R3C, PPP1R3D |
| Paralogs | PPP1R3G, PPP1R3D, PPP1R3C, PPP1R3E, PPP1R3A, PPP1R3F |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the liver and, at lower levels, in skeletal muscle, including in vastus lateralis, gastrocnemius and soleus (at protein level). Highest mRNA levels are observed in skeletal muscle, and only moderate levels in liver and heart. Weak expression in placenta and lung. {ECO:0000269|PubMed:11872655, ECO:0000269|PubMed:17555403}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2EEF (NMR - ) 5ZT0 (X-ray 3.32A ) |
| DBSNP | rs3748140 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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