| Gene Information | |
|---|---|
| Gene Name | TRAT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 186 |
| Protein Names | T-cell receptor-associated transmembrane adapter 1 (T-cell receptor-interacting molecule) (TRIM) (pp29/30) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000163519 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q6PIZ9 |
| Gene Card | TRAT1 |
| Uniprot ID | Q6PIZ9 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.501023084) |
| Ortholog in Animals | Alpaca_ TRAT1 ( ortholog_one2one ) Dog_ TRAT1 ( ortholog_one2one ) GuineaPig_ TRAT1 ( ortholog_one2one ) Macaque_ TRAT1 ( ortholog_one2one ) Mouse_ Trat1 ( ortholog_one2one ) Pig_ TRAT1 ( ortholog_one2one ) Rat_ Trat1 ( ortholog_one2one ) Rabbit_ TRAT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | appendix, lymph.node |
| Tissue Specificity | Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level). {ECO:0000269|PubMed:16160011, ECO:0000269|PubMed:9687533}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs57744779 rs61585973 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:9687533}; Single-pass type III membrane protein {ECO:0000269|PubMed:9687533}. |
| Mouse PG classification | NA |
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