| Gene Information | |
|---|---|
| Gene Name | MYOZ1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 299 |
| Protein Names | Myozenin-1 (Calsarcin-2) (Filamin-, actinin- and telethonin-binding protein) (Protein FATZ) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000177791 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NP98 |
| Gene Card | MYOZ1 |
| Uniprot ID | Q9NP98 |
| Pfam | PF05556 |
| In ASD | no |
| Allosteric Prediction | no (-1.037867908) |
| Ortholog in Animals | Alpaca_ MYOZ1 ( ortholog_one2one ) Dog_ MYOZ1 ( ortholog_one2one ) GuineaPig_ MYOZ1 ( ortholog_one2one ) Macaque_ MYOZ1 ( ortholog_one2one ) Mouse_ Myoz1 ( ortholog_one2one ) Pig_ MYOZ1 ( ortholog_one2one ) Rat_ Myoz1 ( ortholog_one2one ) Rabbit_ MYOZ1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MYOZ3, MYOZ2 |
| Tissue | esophagus, prostate, skeletal.muscle, artery |
| Tissue Specificity | Expressed primarily in skeletal muscle. Detected at lower levels in heart, prostate and pancreas. {ECO:0000269|PubMed:10984498, ECO:0000269|PubMed:11114196, ECO:0000269|PubMed:11171996}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7A8T (X-ray 2.69A ) 7A8U (X-ray 3.80A ) 7ANK (X-ray 3.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. Cell projection, pseudopodium. Note=Localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle. |
| Mouse PG classification | NA |
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