Gene Information
Gene NamePPP2R3C
OrganismHomo sapiens (Human)
Gene Length453
Protein NamesSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma (Protein phosphatase subunit G5PR) (Rhabdomyosarcoma antigen MU-RMS-40.6A/6C)
Target NameNA
Target TypeNA
Gene Age886 ( ENSG00000092020 )
Evolutionary StageEukaryota
AlphaFoldDBQ969Q6
Gene CardPPP2R3C
Uniprot IDQ969Q6
PfamPF17958
In ASDno
Allosteric Predictionyes (0.176671678)
Ortholog in AnimalsAlpaca_ PPP2R3C ( ortholog_one2one )
Dog_ PPP2R3C ( ortholog_one2one )
GuineaPig_ PPP2R3C ( ortholog_one2one )
Macaque_ PPP2R3C ( ortholog_one2one )
Mouse_ Ppp2r3c ( ortholog_one2one )
Pig_ PPP2R3C ( ortholog_one2one )
Rat_ Ppp2r3c ( ortholog_one2one )
Rabbit_ PPP2R3C ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityUbiquitously expressed in brain and other tissues. {ECO:0000269|PubMed:12167160, ECO:0000269|PubMed:15820313}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.022222(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs754106837  rs1566411552  rs1566684983 
Subcellular location [CC]Nucleus {ECO:0000269|PubMed:15820313}. Cytoplasm {ECO:0000269|PubMed:15820313}. Note=Excluded from the nucleoli. Localization is cell cycle-dependent. Localizes to the cytoplasm during cytokinesis. {ECO:0000269|PubMed:15820313}.
Mouse PG classificationNA
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