| Gene Information | |
|---|---|
| Gene Name | PIK3R3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 461 |
| Protein Names | Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK) |
| Target Name | phosphatidylinositol 3-kinase regulatory subunit gamma |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000117461 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q92569 |
| Gene Card | PIK3R3 |
| Uniprot ID | Q92569 |
| Pfam | PF16454; PF00017 |
| In ASD | no |
| Allosteric Prediction | yes (1.032716886) |
| Ortholog in Animals | Alpaca_ PIK3R3 ( ortholog_one2one ) Dog_ PIK3R3 ( ortholog_one2one ) GuineaPig_ PIK3R3 ( ortholog_one2one ) Macaque_ PIK3R3 ( ortholog_one2one ) Mouse_ Pik3r3 ( ortholog_one2one ) Pig_ PIK3R3 ( ortholog_one2one ) Rat_ Pik3r3 ( ortholog_one2one ) Rabbit_ PIK3R3 ( ortholog_one2one ) |
| Ohnologs | PIK3R2, PIK3R1 |
| Paralogs | PIK3R2, PIK3R1 |
| Tissue | NA |
| Tissue Specificity | Highest levels in brain and testis. Lower levels in adipose tissue, kidney, heart, lung and skeletal muscle. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002061(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs785467 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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