| Gene Information | |
|---|---|
| Gene Name | KDM4E |
| Organism | Homo sapiens (Human) |
| Gene Length | 506 |
| Protein Names | Lysine-specific demethylase 4E (EC 1.14.11.66) (KDM4D-like protein) (Lysine-specific demethylase 4D-like) ([histone H3]-trimethyl-L-lysine(9) demethylase 4E) |
| Target Name | lysine-specific demethylase 4e |
| Target Type | Patented-recorded target |
| Gene Age | 36 ( ENSG00000235268 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | B2RXH2 |
| Gene Card | KDM4E |
| Uniprot ID | B2RXH2 |
| Pfam | PF02373; PF02375 |
| In ASD | no |
| Allosteric Prediction | no (-0.495033269) |
| Ortholog in Animals | Alpaca_ KDM4E ( ortholog_one2one ) Macaque_ KDM4E ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KDM4F, JARID2, KDM4C, KDM4B, KDM4D, KDM5B, KDM5C, KDM5D, KDM4A, KDM5A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2W2I (X-ray 2.10A ) |
| DBSNP | rs12798990 rs2257265 rs10752685 rs16921260 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00537}. |
| Mouse PG classification | NA |
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