| Gene Information | |
|---|---|
| Gene Name | RELT |
| Organism | Homo sapiens (Human) |
| Gene Length | 430 |
| Protein Names | Tumor necrosis factor receptor superfamily member 19L (Receptor expressed in lymphoid tissues) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000054967 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q969Z4 |
| Gene Card | RELT |
| Uniprot ID | Q969Z4 |
| Pfam | PF12606 |
| In ASD | no |
| Allosteric Prediction | no (-0.964942415) |
| Ortholog in Animals | Alpaca_ RELT ( ortholog_one2one ) Dog_ RELT ( ortholog_one2one ) GuineaPig_ RELT ( ortholog_one2one ) Macaque_ RELT ( ortholog_one2one ) Mouse_ Relt ( ortholog_one2one ) Pig_ RELT ( ortholog_one2one ) Rat_ Relt ( ortholog_one2one ) Rabbit_ RELT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TNFRSF25, TNFRSF6B, CD40, TNFRSF21, TNFRSF1A, TNFRSF10C, TNFRSF11B, TNFRSF10B, TNFRSF11A, CD27, NGFR, FAS, TNFRSF10A, TNFRSF9, TNFRSF18, TNFRSF8, LTBR, TNFRSF10D, TNFRSF4, TNFRSF14, TNFRSF1B |
| Tissue | bone.marrow, whole.blood |
| Tissue Specificity | Spleen, lymph node, brain, breast and peripheral blood leukocytes (at protein level) (PubMed:28688764). Expressed highly in bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in kidney and pancreas. {ECO:0000269|PubMed:16389068, ECO:0000269|PubMed:28688764}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12362779 rs762816338 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:16389068}; Single-pass type I membrane protein {ECO:0000269|PubMed:16389068}. Cytoplasm {ECO:0000269|PubMed:16389068}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:22052202}. |
| Mouse PG classification | NA |
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