| Gene Information | |
|---|---|
| Gene Name | PPIP5K2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1243 |
| Protein Names | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (hsVIP2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000145725 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43314 |
| Gene Card | PPIP5K2 |
| Uniprot ID | O43314 |
| Pfam | PF00328; PF18086 |
| In ASD | no |
| Allosteric Prediction | no (-0.521351516) |
| Ortholog in Animals | Alpaca_ PPIP5K2 ( ortholog_one2one ) Dog_ PPIP5K2 ( ortholog_one2one ) GuineaPig_ PPIP5K2 ( ortholog_one2one ) Macaque_ PPIP5K2 ( ortholog_one2one ) Mouse_ Ppip5k2 ( ortholog_one2one ) Pig_ PPIP5K2 ( ortholog_one2one ) Rat_ Ppip5k2 ( ortholog_one2one ) Rabbit_ PPIP5K2 ( ortholog_one2one ) |
| Ohnologs | PPIP5K1 |
| Paralogs | PPIP5K1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3T54 (X-ray 1.90A ) 3T7A (X-ray 1.70A ) 3T99 (X-ray 2.10A ) 3T9A (X-ray 1.80A ) 3T9B (X-ray 1.85A ) 3T9C (X-ray 1.90A ) 3T9D (X-ray 1.85A ) 3T9E (X-ray 1.90A ) 3T9F (X-ray 2.00A ) 4HN2 (X-ray 1.90A ) 4NZM (X-ray 2.00A ) 4NZN (X-ray 1.75A ) 4NZO (X-ray 1.90A ) 4Q4C (X-ray 1.90A ) 4Q4D (X-ray 1.85A ) 5BYA (X-ray 1.90A ) 5BYB (X-ray 2.30A ) 5DGH (X-ray 2.10A ) 5DGI (X-ray 1.85A ) 6N5C (X-ray 1.95A ) |
| DBSNP | rs548137246 rs17155115 rs12519525 rs12520040 rs17155138 rs17155147 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:17690096}. |
| Mouse PG classification | NA |
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