| Gene Information | |
|---|---|
| Gene Name | PPIH |
| Organism | Homo sapiens (Human) |
| Gene Length | 177 |
| Protein Names | Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP) |
| Target Name | peptidyl-prolyl cis-trans isomerase h |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000171960 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43447 |
| Gene Card | PPIH |
| Uniprot ID | O43447 |
| Pfam | PF00160 |
| In ASD | no |
| Allosteric Prediction | no (-0.643351263) |
| Ortholog in Animals | Alpaca_ PPIH ( ortholog_one2one ) Dog_ PPIH ( ortholog_one2one ) GuineaPig_ PPIH ( ortholog_one2one ) Macaque_ PPIH ( ortholog_one2one ) Mouse_ Gm7879 ( ortholog_one2one ) Pig_ PPIH ( ortholog_one2one ) Rat_ Ppih ( ortholog_one2one ) Rabbit_ PPIH ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PPIL4, PPIL6, CWC27, PPIB, NKTR, PPIAL4A, PPIAL4E, PPIAL4F, PPIAL4D, PPIAL4G, PPIAL4C, PPIAL4H, PPIA, PPIC, PPIE, PPIG, PPID, PPWD1, PPIF, PPIL2, PPIL3, PPIL1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.137429(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1MZW (X-ray 2.00A ) 1QOI (X-ray 2.00A ) 5O9Z (EM 4.50A ) 6AHD (EM 3.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus speckle {ECO:0000269|PubMed:9570313}. Cytoplasm {ECO:0000269|PubMed:9570313}. Note=Colocalizes with spliceosomal snRNPs. A small proportion may also be cytoplasmic. |
| Mouse PG classification | NA |
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