| Gene Information | |
|---|---|
| Gene Name | PPIF |
| Organism | Homo sapiens (Human) |
| Gene Length | 207 |
| Protein Names | Peptidyl-prolyl cis-trans isomerase F, mitochondrial (PPIase F) (EC 5.2.1.8) (Cyclophilin D) (CyP-D) (CypD) (Cyclophilin F) (Mitochondrial cyclophilin) (CyP-M) (Rotamase F) |
| Target Name | peptidyl-prolyl cis-trans isomerase f, mitochondrial |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000108179 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P30405 |
| Gene Card | PPIF |
| Uniprot ID | P30405 |
| Pfam | PF00160 |
| In ASD | no |
| Allosteric Prediction | yes (0.455086139) |
| Ortholog in Animals | Alpaca_ PPIF ( ortholog_one2one ) Dog_ PPIF ( ortholog_one2one ) GuineaPig_ PPIF ( ortholog_one2one ) Macaque_ PPIF ( ortholog_one2one ) Mouse_ Ppif ( ortholog_one2one ) Pig_ PPIF ( ortholog_one2one ) Rat_ Ppif ( ortholog_one2one ) Rabbit_ PPIF ( ortholog_one2one ) |
| Ohnologs | PPIA |
| Paralogs | PPIH, PPIL4, PPIL6, CWC27, PPIB, NKTR, PPIAL4A, PPIAL4E, PPIAL4F, PPIAL4D, PPIAL4G, PPIAL4C, PPIAL4H, PPIA, PPIC, PPIE, PPIG, PPID, PPWD1, PPIL2, PPIL3, PPIL1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.057662(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2BIT (X-ray 1.71A ) 2BIU (X-ray 1.71A ) 2Z6W (X-ray 0.96A ) 3QYU (X-ray 1.54A ) 3R49 (X-ray 1.77A ) 3R4G (X-ray 1.05A ) 3R54 (X-ray 1.35A ) 3R56 (X-ray 1.40A ) 3R57 (X-ray 1.71A ) 3R59 (X-ray 1.10A ) 3RCF (X-ray 1.15A ) 3RCG (X-ray 0.97A ) 3RCI (X-ray 1.44A ) 3RCK (X-ray 1.26A ) 3RCL (X-ray 1.70A ) 3RD9 (X-ray 1.40A ) 3RDA (X-ray 1.07A ) 3RDB (X-ray 1.55A ) 3RDC (X-ray 1.94A ) 4J58 (X-ray 1.28A ) 4J59 (X-ray 1.92A ) 4J5A (X-ray 1.58A ) 4J5B (X-ray 2.01A ) 4J5C (X-ray 1.03A ) 4J5D (X-ray 1.32A ) 4J5E (X-ray 0.99A ) 4O8H (X-ray 0.85A ) 4O8I (X-ray 1.45A ) 4XNC (X-ray 2.23A ) 4ZSC (X-ray 1.50A ) 4ZSD (X-ray 1.45A ) 5A0E (X-ray 1.25A ) 5CBT (X-ray 1.45A ) 5CBU (X-ray 1.40A ) 5CBV (X-ray 1.80A ) 5CBW (X-ray 1.80A ) 5CCN (X-ray 1.80A ) 5CCQ (X-ray 1.80A ) 5CCR (X-ray 1.90A ) 5CCS (X-ray 2.10A ) 6R8L (X-ray 1.64A ) 6R8O (X-ray 1.36A ) 6R8W (X-ray 1.40A ) 6R9S (X-ray 2.00A ) 6R9U (X-ray 1.26A ) 6R9X (X-ray 1.66A ) 6RA1 (X-ray 2.00A ) 6Y3E (X-ray 1.45A ) 6YBM (X-ray 1.41A ) 7OGI (X-ray 1.01A ) 7TGS (X-ray 1.75A ) 7TGT (X-ray 1.06A ) 7TGU (X-ray 1.21A ) 7TGV (X-ray 1.46A ) 7TH1 (X-ray 1.52A ) 7TH6 (X-ray 0.97A ) 7TH7 (X-ray 1.30A ) 7THC (X-ray 1.57A ) 7THD (X-ray 1.16A ) 7THF (X-ray 1.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion matrix {ECO:0000269|PubMed:10406942}. |
| Mouse PG classification | NA |
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