Gene Information
Gene NamePPID
OrganismHomo sapiens (Human)
Gene Length370
Protein NamesPeptidyl-prolyl cis-trans isomerase D (PPIase D) (EC 5.2.1.8) (40 kDa peptidyl-prolyl cis-trans isomerase) (Cyclophilin-40) (CYP-40) (Cyclophilin-related protein) (Rotamase D)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000171497 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ08752
Gene CardPPID
Uniprot IDQ08752
PfamPF00160; PF13176
In ASDno
Allosteric Predictionyes (0.45866033)
Ortholog in AnimalsAlpaca_ PPID ( ortholog_one2one )
Dog_ PPID ( ortholog_one2one )
GuineaPig_ PPID ( ortholog_one2one )
Mouse_ Ppid ( ortholog_one2one )
Pig_ PPID ( ortholog_one2one )
Rat_ Ppid ( ortholog_one2many )
Rat_ Ppidl1 ( ortholog_one2many )
Rabbit_ PPID ( ortholog_one2one )
OhnologsNA
ParalogsPPIH, PPIL4, PPIL6, CWC27, PPIB, NKTR, PPIAL4A, PPIAL4E, PPIAL4F, PPIAL4D, PPIAL4G, PPIAL4C, PPIAL4H, PPIA, PPIC, PPIE, PPIG, PPWD1, PPIF, PPIL2, PPIL3, PPIL1
TissueNA
Tissue SpecificityWidely expressed.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001823(Rat);0.030769(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2070631  rs2230222  rs9410  rs17843956 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:11525244, ECO:0000269|PubMed:18708059}. Nucleus, nucleolus {ECO:0000269|PubMed:11525244, ECO:0000269|PubMed:18708059}. Nucleus, nucleoplasm {ECO:0000269|PubMed:11525244, ECO:0000269|PubMed:18708059}.
Mouse PG classificationNA
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