| Gene Information | |
|---|---|
| Gene Name | PPEF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 653 |
| Protein Names | Serine/threonine-protein phosphatase with EF-hands 1 (PPEF-1) (EC 3.1.3.16) (Protein phosphatase with EF calcium-binding domain) (PPEF) (Serine/threonine-protein phosphatase 7) (PP7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000086717 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O14829 |
| Gene Card | PPEF1 |
| Uniprot ID | O14829 |
| Pfam | PF13499; PF00612; PF00149; PF08321 |
| In ASD | no |
| Allosteric Prediction | yes (0.093846819) |
| Ortholog in Animals | Alpaca_ PPEF1 ( ortholog_one2one ) Dog_ PPEF1 ( ortholog_one2one ) GuineaPig_ PPEF1 ( ortholog_one2one ) Macaque_ PPEF1 ( ortholog_one2one ) Mouse_ Ppef1 ( ortholog_one2one ) Pig_ PPEF1 ( ortholog_one2one ) Rat_ Ppef1 ( ortholog_one2one ) Rabbit_ PPEF1 ( ortholog_one2one ) |
| Ohnologs | PPEF2 |
| Paralogs | PPP3CC, PPP3CB, PPP6C, PPP5C, PPP2CB, PPP2CA, PPEF2, PPP4C, PPP3CA, PPP1CA, PPP1CC, PPP1CB |
| Tissue | testis |
| Tissue Specificity | Detected in retina and retinal derived Y-79 retinoblastoma cells. Also found in fetal brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1065074 rs11796620 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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