| Gene Information | |
|---|---|
| Gene Name | PPARGC1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 1023 |
| Protein Names | Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PGC-1-beta) (PPAR-gamma coactivator 1-beta) (PPARGC-1-beta) (PGC-1-related estrogen receptor alpha coactivator) |
| Target Name | peroxisome proliferator-activated receptor gamma coactivator 1-beta |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000155846 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q86YN6 |
| Gene Card | PPARGC1B |
| Uniprot ID | Q86YN6 |
| Pfam | PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-0.084042475) |
| Ortholog in Animals | Alpaca_ PPARGC1B ( ortholog_one2one ) Dog_ PPARGC1B ( ortholog_one2one ) GuineaPig_ PPARGC1B ( ortholog_one2one ) Macaque_ PPARGC1B ( ortholog_one2one ) Mouse_ Ppargc1b ( ortholog_one2one ) Pig_ PPARGC1B ( ortholog_one2one ) Rat_ Ppargc1b ( ortholog_one2one ) Rabbit_ PPARGC1B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PPARGC1A, PPRC1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous with higher expression in heart, brain and skeletal muscle. {ECO:0000269|PubMed:11854298, ECO:0000269|PubMed:12678921}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 3SP6 (X-ray 2.21A ) 6D0Y (X-ray 2.68A ) |
| DBSNP | rs7732671 rs45520937 rs17572019 rs11959820 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11854298}. |
| Mouse PG classification | LPG |
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