| Gene Information | |
|---|---|
| Gene Name | PPA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 334 |
| Protein Names | Inorganic pyrophosphatase 2, mitochondrial (EC 3.6.1.1) (Pyrophosphatase SID6-306) (Pyrophosphate phospho-hydrolase 2) (PPase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000138777 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9H2U2 |
| Gene Card | PPA2 |
| Uniprot ID | Q9H2U2 |
| Pfam | PF00719 |
| In ASD | no |
| Allosteric Prediction | no (-0.90302038) |
| Ortholog in Animals | Alpaca_ PPA2 ( ortholog_one2one ) GuineaPig_ PPA2 ( ortholog_one2one ) Macaque_ PPA2 ( ortholog_one2one ) Mouse_ Ppa2 ( ortholog_one2one ) Pig_ PPA2 ( ortholog_one2one ) Rat_ Ppa2 ( ortholog_one2one ) Rabbit_ PPA2 ( ortholog_one2one ) |
| Ohnologs | PPA1 |
| Paralogs | PPA1 |
| Tissue | NA |
| Tissue Specificity | Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium. {ECO:0000269|PubMed:15210126}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);0.013333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1057517679 rs1057517680 rs139076647 rs546693824 rs146013446 rs138215926 rs13787 rs1057517678 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:27523597}. |
| Mouse PG classification | NA |
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