| Gene Information | |
|---|---|
| Gene Name | PPA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 289 |
| Protein Names | Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000180817 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q15181 |
| Gene Card | PPA1 |
| Uniprot ID | Q15181 |
| Pfam | PF00719 |
| In ASD | no |
| Allosteric Prediction | yes (0.200253745) |
| Ortholog in Animals | Alpaca_ PPA1 ( ortholog_one2one ) GuineaPig_ PPA1 ( ortholog_one2one ) Macaque_ PPA1 ( ortholog_one2one ) Mouse_ Ppa1 ( ortholog_one2one ) Pig_ PPA1 ( ortholog_one2one ) Rat_ Ppa1 ( ortholog_one2one ) Rabbit_ PPA1 ( ortholog_one2one ) |
| Ohnologs | PPA2 |
| Paralogs | PPA2 |
| Tissue | NA |
| Tissue Specificity | Expressed ubiquitously. {ECO:0000269|PubMed:10542310}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.015385(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6C45 (X-ray 2.39A ) 7BTN (X-ray 2.38A ) 7CMO (X-ray 3.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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