| Gene Information | |
|---|---|
| Gene Name | SRPRA |
| Organism | Homo sapiens (Human) |
| Gene Length | 638 |
| Protein Names | Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000182934 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P08240 |
| Gene Card | SRPRA |
| Uniprot ID | P08240 |
| Pfam | PF04086; PF00448; PF02881 |
| In ASD | no |
| Allosteric Prediction | no (-1.139786564) |
| Ortholog in Animals | Alpaca_ SRPRA ( ortholog_one2one ) Dog_ SRPRA ( ortholog_one2one ) GuineaPig_ SRPRA ( ortholog_one2one ) Macaque_ SRPRA ( ortholog_one2one ) Mouse_ Srpr ( ortholog_one2one ) Pig_ SRPRA ( ortholog_one2one ) Rat_ Srpra ( ortholog_one2one ) Rabbit_ SRPRA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SRP54 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001398(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2FH5 (X-ray 2.45A ) 2GO5 (EM 7.40A ) 5L3Q (X-ray 3.20A ) 6Y32 (X-ray 2.60A ) 7NFX (EM 3.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P32916}; Peripheral membrane protein {ECO:0000250|UniProtKB:P32916}; Cytoplasmic side {ECO:0000250|UniProtKB:P32916}. Note=Thought to be anchored in the membrane through an interaction with SR-beta, which contains a bona fide transmembrane domain. {ECO:0000250|UniProtKB:P32916}. |
| Mouse PG classification | NA |
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