| Gene Information | |
|---|---|
| Gene Name | SLC17A4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 497 |
| Protein Names | Probable small intestine urate exporter (Solute carrier family 17 member 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000146039 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9Y2C5 |
| Gene Card | SLC17A4 |
| Uniprot ID | Q9Y2C5 |
| Pfam | PF07690 |
| In ASD | no |
| Allosteric Prediction | no (-0.699348446) |
| Ortholog in Animals | Alpaca_ SLC17A4 ( ortholog_one2one ) Dog_ SLC17A4 ( ortholog_one2one ) GuineaPig_ SLC17A4 ( ortholog_one2one ) Macaque_ SLC17A4 ( ortholog_one2one ) Mouse_ Slc17a4 ( ortholog_one2one ) Pig_ SLC17A4 ( ortholog_one2one ) Rat_ Slc17a4 ( ortholog_one2one ) Rabbit_ SLC17A4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC17A8, SLC37A4, SLC17A3, SLC17A6, SLC17A7, SLC17A9, SLC17A2, SLC37A1, SLC17A1, SLC37A3, SLC17A5, SLC37A2 |
| Tissue | NA |
| Tissue Specificity | Abundantly expressed in pancreas, liver, colon and small intestine, less in kidney. Not detected in the adrenal glands, brain, placenta, heart, testis, skeletal muscle, and lungs. {ECO:0000269|PubMed:10319585, ECO:0000269|PubMed:22460716}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11754288 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000269|PubMed:22460716}; Multi-pass membrane protein {ECO:0000269|PubMed:22460716}. Cell membrane {ECO:0000269|PubMed:22460716}; Multi-pass membrane protein {ECO:0000269|PubMed:22460716}. Note=Apical in the intestinal brush border. |
| Mouse PG classification | NA |
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