| Gene Information | |
|---|---|
| Gene Name | SPATA18 |
| Organism | Homo sapiens (Human) |
| Gene Length | 538 |
| Protein Names | Mitochondria-eating protein (Spermatogenesis-associated protein 18) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000163071 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8TC71 |
| Gene Card | SPATA18 |
| Uniprot ID | Q8TC71 |
| Pfam | PF16026 |
| In ASD | no |
| Allosteric Prediction | no (-1.244680277) |
| Ortholog in Animals | Alpaca_ SPATA18 ( ortholog_one2one ) Dog_ SPATA18 ( ortholog_one2one ) Macaque_ SPATA18 ( ortholog_one2one ) Mouse_ Spata18 ( ortholog_one2one ) Pig_ SPATA18 ( ortholog_one2one ) Rat_ Spata18 ( ortholog_one2one ) Rabbit_ SPATA18 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3860707 rs11558773 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21264228, ECO:0000269|PubMed:22292033}. Mitochondrion outer membrane {ECO:0000269|PubMed:21264228, ECO:0000269|PubMed:22292033}. Note=Localizes to the cytoplasm under normal conditions (PubMed:21264228). Relocalizes to mitochondrion outer membrane following cellular stress. Colocalizes with BNIP3 and BNIP3L at the mitochondrion outer membrane (PubMed:22292033). {ECO:0000269|PubMed:21264228, ECO:0000269|PubMed:22292033}. |
| Mouse PG classification | NA |
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