| Gene Information | |
|---|---|
| Gene Name | TSPAN7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 249 |
| Protein Names | Tetraspanin-7 (Tspan-7) (Cell surface glycoprotein A15) (Membrane component chromosome X surface marker 1) (T-cell acute lymphoblastic leukemia-associated antigen 1) (TALLA-1) (Transmembrane 4 superfamily member 2) (CD antigen CD231) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000156298 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P41732 |
| Gene Card | TSPAN7 |
| Uniprot ID | P41732 |
| Pfam | PF00335 |
| In ASD | no |
| Allosteric Prediction | no (-0.835233133) |
| Ortholog in Animals | Alpaca_ TSPAN7 ( ortholog_one2one ) Dog_ TSPAN7 ( ortholog_one2one ) GuineaPig_ TSPAN7 ( ortholog_one2one ) Macaque_ TSPAN7 ( ortholog_one2one ) Mouse_ Tspan7 ( ortholog_one2one ) Pig_ TSPAN7 ( ortholog_one2one ) Rat_ AABR07004190.1 ( ortholog_one2many ) Rat_ Tspan7 ( ortholog_one2many ) Rabbit_ TSPAN7 ( ortholog_one2one ) |
| Ohnologs | TSPAN6 |
| Paralogs | ROM1, TSPAN12, CD63, TSPAN10, CD9, TSPAN6, TSPAN5, CD37, CD151, TSPAN4, TSPAN1, TSPAN31, UPK1A, TSPAN17, TSPAN11, TSPAN32, TSPAN8, TSPAN13, TSPAN2, CD53, TSPAN9, TSPAN18, CD81, CD82, TSPAN16, TSPAN19, UPK1B, TSPAN3, TSPAN14, TSPAN15, PRPH2, TSPAN33 |
| Tissue | NA |
| Tissue Specificity | Not solely expressed in T-cells. Expressed in acute myelocytic leukemia cells of some patients. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17851592 rs17851593 rs104894951 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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