| Gene Information | |
|---|---|
| Gene Name | SERBP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 408 |
| Protein Names | Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA-binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000142864 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NC51 |
| Gene Card | SERBP1 |
| Uniprot ID | Q8NC51 |
| Pfam | PF04774; PF16174 |
| In ASD | no |
| Allosteric Prediction | no (-0.870873596) |
| Ortholog in Animals | Alpaca_ SERBP1 ( ortholog_one2one ) Dog_ SERBP1 ( ortholog_one2one ) GuineaPig_ SERBP1 ( ortholog_one2one ) Macaque_ SERBP1 ( ortholog_one2one ) Mouse_ Serbp1 ( ortholog_one2one ) Pig_ SERBP1 ( ortholog_one2one ) Rat_ Serbp1 ( ortholog_one2one ) Rabbit_ SERBP1 ( ortholog_one2one ) |
| Ohnologs | HABP4 |
| Paralogs | HABP4 |
| Tissue | NA |
| Tissue Specificity | Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain. {ECO:0000269|PubMed:12505151}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.045208(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4V6X (EM 5.00A ) 6Z6M (EM 3.10A ) 6Z6N (EM 2.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12505151, ECO:0000269|PubMed:28695742}. Nucleus {ECO:0000269|PubMed:12505151, ECO:0000269|PubMed:28695742}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:12505151}. |
| Mouse PG classification | NA |
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