| Gene Information | |
|---|---|
| Gene Name | RIF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 769 |
| Protein Names | Ligand-dependent nuclear receptor-interacting factor 1 (HP1-binding protein enriched in inactive X chromosome protein 1) (HBiX1) (Receptor-interacting factor 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000080345 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q5T3J3 |
| Gene Card | LRIF1 |
| Uniprot ID | Q5T3J3 |
| Pfam | PF15741 |
| In ASD | no |
| Allosteric Prediction | yes (0.095047118) |
| Ortholog in Animals | Alpaca_ RIF1 ( ortholog_one2one ) Dog_ RIF1 ( ortholog_one2one ) GuineaPig_ RIF1 ( ortholog_one2one ) Macaque_ RIF1 ( ortholog_one2one ) Mouse_ Rif1 ( ortholog_one2one ) Pig_ RIF1 ( ortholog_one2one ) Rat_ Rif1 ( ortholog_one2one ) Rabbit_ RIF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed, with the highest expression levels in heart, liver and placenta. {ECO:0000269|PubMed:17455211}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2232041 rs2232045 rs2232047 |
| Subcellular location [CC] | Chromosome {ECO:0000269|PubMed:23542155}. Nucleus matrix {ECO:0000269|PubMed:17455211}. Note=Localizes to Barr body; recruited by SMCHD1. {ECO:0000269|PubMed:23542155}. |
| Mouse PG classification | NA |
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