| Gene Information | |
|---|---|
| Gene Name | TBL1XR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 514 |
| Protein Names | F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000177565 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9BZK7 |
| Gene Card | TBL1XR1 |
| Uniprot ID | Q9BZK7 |
| Pfam | PF08513; PF00400 |
| In ASD | no |
| Allosteric Prediction | yes (0.384596247) |
| Ortholog in Animals | Alpaca_ TBL1XR1 ( ortholog_one2one ) Dog_ TBL1XR1 ( ortholog_one2one ) GuineaPig_ TBL1XR1 ( ortholog_one2one ) Macaque_ TBL1XR1 ( ortholog_one2one ) Mouse_ Tbl1xr1 ( ortholog_one2one ) Pig_ TBL1XR1 ( ortholog_one2one ) Rat_ Tbl1xr1 ( ortholog_one2one ) Rabbit_ TBL1XR1 ( ortholog_one2one ) |
| Ohnologs | TBL1Y, TBL1X |
| Paralogs | TBL1X, TBL1Y |
| Tissue | NA |
| Tissue Specificity | Widely expressed including the pituitary, hypothalamus, white and brown adipose tissue, muscle and liver. {ECO:0000269|PubMed:26769062}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.121054(Rat);0.037412(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 4LG9 (X-ray 2.28A ) |
| DBSNP | rs786205859 rs372813783 rs878854401 rs747932785 rs781011308 rs878854402 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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