| Gene Information | |
|---|---|
| Gene Name | KIAA0305 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1539 |
| Protein Names | Zinc finger FYVE domain-containing protein 16 (Endofin) (Endosome-associated FYVE domain protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q7Z3T8 |
| Gene Card | ZFYVE16 |
| Uniprot ID | Q7Z3T8 |
| Pfam | PF11979; PF01363 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level in heart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes. {ECO:0000269|PubMed:11546807}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3T7L (X-ray 1.09A ) 5MK0 (X-ray 1.76A ) |
| DBSNP | rs6893297 rs2544600 rs752702732 rs259028 rs249038 rs16877836 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11546807}. Early endosome membrane {ECO:0000269|PubMed:11546807}; Peripheral membrane protein {ECO:0000269|PubMed:11546807}. Note=Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate (PI3P). |
| Mouse PG classification | NA |
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