| Gene Information | |
|---|---|
| Gene Name | AKAP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 853 |
| Protein Names | A-kinase anchor protein 3 (AKAP-3) (A-kinase anchor protein 110 kDa) (AKAP 110) (Cancer/testis antigen 82) (CT82) (Fibrous sheath protein of 95 kDa) (FSP95) (Fibrousheathin I) (Fibrousheathin-1) (Protein kinase A-anchoring protein 3) (PRKA3) (Sperm oocyte-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000111254 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O75969 |
| Gene Card | AKAP3 |
| Uniprot ID | O75969 |
| Pfam | PF05716; PF10522 |
| In ASD | no |
| Allosteric Prediction | no (-0.999741592) |
| Ortholog in Animals | Alpaca_ AKAP3 ( ortholog_one2one ) Dog_ AKAP3 ( ortholog_one2one ) GuineaPig_ AKAP3 ( ortholog_one2one ) Macaque_ AKAP3 ( ortholog_one2one ) Mouse_ Akap3 ( ortholog_one2one ) Pig_ AKAP3 ( ortholog_one2one ) Rat_ Akap3 ( ortholog_one2one ) Rabbit_ AKAP3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AKAP4, AKAP11, SPHKAP |
| Tissue | testis |
| Tissue Specificity | Testis specific; only expressed in spermatids. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.15(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2072355 rs11063266 rs12366671 rs1990312 rs1990313 rs2041291 rs2041290 rs2072357 rs143517596 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. Note=Ribs of the fibrous sheath in the principal piece of the sperm tail. Dorsal margin of the acrosomal segment. |
| Mouse PG classification | NA |
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