| Gene Information | |
|---|---|
| Gene Name | PIK3R2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 728 |
| Protein Names | Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase regulatory subunit beta) (PI3K regulatory subunit beta) (PtdIns-3-kinase regulatory subunit beta) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta) (PI3-kinase subunit p85-beta) (PtdIns-3-kinase regulatory subunit p85-beta) |
| Target Name | phosphatidylinositol 3-kinase regulatory subunit beta |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000105647 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O00459 |
| Gene Card | PIK3R2 |
| Uniprot ID | O00459 |
| Pfam | PF16454; PF00620; PF00017 |
| In ASD | no |
| Allosteric Prediction | yes (1.325570379) |
| Ortholog in Animals | Alpaca_ PIK3R2 ( ortholog_one2one ) Dog_ PIK3R2 ( ortholog_one2one ) GuineaPig_ PIK3R2 ( ortholog_one2one ) Macaque_ PIK3R2 ( ortholog_one2one ) Mouse_ Pik3r2 ( ortholog_one2one ) Pig_ PIK3R2 ( ortholog_one2one ) Rat_ Pik3r2 ( ortholog_one2one ) |
| Ohnologs | PIK3R3, PIK3R1 |
| Paralogs | PIK3R3, PIK3R1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003682(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KT1 (NMR - ) 2XS6 (X-ray 2.09A ) 3MTT (X-ray 3.30A ) 3O5Z (X-ray 2.01A ) 6OX7 (X-ray 2.75A ) 6U28 (X-ray 2.95A ) 7RCH (X-ray 3.10A ) 7RNU (X-ray 1.45A ) |
| DBSNP | rs2241088 rs1011320 rs587776934 rs886041591 rs587777624 rs372272045 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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