| Gene Information | |
|---|---|
| Gene Name | ASIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 132 |
| Protein Names | Agouti-signaling protein (ASP) (Agouti switch protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000101440 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P42127 |
| Gene Card | ASIP |
| Uniprot ID | P42127 |
| Pfam | PF05039 |
| In ASD | no |
| Allosteric Prediction | no (-0.463138561) |
| Ortholog in Animals | Alpaca_ ASIP ( ortholog_one2one ) Dog_ ASIP ( ortholog_one2one ) GuineaPig_ ASIP ( ortholog_one2one ) Macaque_ ASIP ( ortholog_one2one ) Mouse_ a ( ortholog_one2one ) Pig_ ASIP ( ortholog_one2one ) Rat_ Asip ( ortholog_one2one ) Rabbit_ asip ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AGRP |
| Tissue | ovary |
| Tissue Specificity | Expressed in adipose tissue, testis, ovary and heart and at lower levels in liver, kidney and foreskin. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1Y7J (NMR - ) 1Y7K (NMR - ) 2KZA (NMR - ) 2L1J (NMR - ) |
| DBSNP | rs2296151 rs1129414 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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