| Gene Information | |
|---|---|
| Gene Name | POU2AF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 256 |
| Protein Names | POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (BOB-1) (OCA-B) (OCT-binding factor 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000110777 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q16633 |
| Gene Card | POU2AF1 |
| Uniprot ID | Q16633 |
| Pfam | PF09310 |
| In ASD | no |
| Allosteric Prediction | no (-0.930294993) |
| Ortholog in Animals | Alpaca_ POU2AF1 ( ortholog_one2one ) Dog_ POU2AF1 ( ortholog_one2one ) GuineaPig_ POU2AF1 ( ortholog_one2one ) Macaque_ POU2AF1 ( ortholog_one2one ) Mouse_ Pou2af1 ( ortholog_one2one ) Pig_ POU2AF1 ( ortholog_one2one ) Rat_ Pou2af1 ( ortholog_one2one ) Rabbit_ POU2AF1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | spleen |
| Tissue Specificity | B-cell specific (PubMed:7779176, PubMed:7859290). Detected in mainly in spleen, but also in thymus, periphral blood leukocyte and small intestine (PubMed:7779176, PubMed:7859290). {ECO:0000269|PubMed:7779176, ECO:0000269|PubMed:7859290}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1CQT (X-ray 3.20A ) |
| DBSNP | rs1042750 rs1042751 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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