Gene Information
Gene NameCERS5
OrganismHomo sapiens (Human)
Gene Length392
Protein NamesCeramide synthase 5 (CerS5) (LAG1 longevity assurance homolog 5) (Sphingoid base N-palmitoyltransferase CERS5) (EC 2.3.1.291) (Sphingosine N-acyltransferase CERS5) (EC 2.3.1.24)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000139624 )
Evolutionary StageEukaryota
AlphaFoldDBQ8N5B7
Gene CardCERS5
Uniprot IDQ8N5B7
PfamPF00046; PF03798
In ASDno
Allosteric Predictionno (-0.487341886)
Ortholog in AnimalsAlpaca_ CERS5 ( ortholog_one2one )
Dog_ CERS5 ( ortholog_one2one )
GuineaPig_ CERS5 ( ortholog_one2one )
Mouse_ Cers5 ( ortholog_one2one )
Pig_ CERS5 ( ortholog_one2one )
Rat_ Cers5 ( ortholog_one2one )
Rabbit_ CERS5 ( ortholog_one2one )
OhnologsCERS3, CERS2, CERS6
ParalogsCERS6, CERS3, CERS4, CERS2, CERS1
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs7302981 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9D6K9};
Multi-pass membrane protein {ECO:0000255}.
Mouse PG classificationNA
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