| Gene Information | |
|---|---|
| Gene Name | RASGRP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 690 |
| Protein Names | Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000152689 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8IV61 |
| Gene Card | RASGRP3 |
| Uniprot ID | Q8IV61 |
| Pfam | PF00130; PF13202; PF00617 |
| In ASD | no |
| Allosteric Prediction | yes (0.788310077) |
| Ortholog in Animals | Alpaca_ RASGRP3 ( ortholog_one2one ) Dog_ RASGRP3 ( ortholog_one2one ) GuineaPig_ RASGRP3 ( ortholog_one2one ) Macaque_ RASGRP3 ( ortholog_one2one ) Mouse_ Rasgrp3 ( ortholog_one2one ) Pig_ RASGRP3 ( ortholog_one2one ) Rat_ Rasgrp3 ( ortholog_one2one ) Rabbit_ RASGRP3 ( ortholog_one2one ) |
| Ohnologs | RASGRP2, RASGRP4, RASGRP1 |
| Paralogs | RALGDS, RASGEF1A, RASGRF2, SOS2, RAPGEF3, RAPGEF6, RASGRF1, RAPGEF2, RGL1, RAPGEF1, RASGEF1B, RASGRP2, RGL2, SOS1, RGL3, RALGPS1, RALGPS2, RAPGEF4, RGL4, RASGRP4, RAPGEFL1, RAPGEF5, RASGRP1, RASGEF1C |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs13388394 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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