| Gene Information | |
|---|---|
| Gene Name | PIK3C2G |
| Organism | Homo sapiens (Human) |
| Gene Length | 1445 |
| Protein Names | Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma (PI3K-C2-gamma) (PtdIns-3-kinase C2 subunit gamma) (EC 2.7.1.137) (EC 2.7.1.154) (Phosphoinositide 3-kinase-C2-gamma) |
| Target Name | phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit gamma |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000139144 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O75747 |
| Gene Card | PIK3C2G |
| Uniprot ID | O75747 |
| Pfam | PF00168; PF00454; PF00794; PF00613; PF00787 |
| In ASD | no |
| Allosteric Prediction | no (-0.044875732) |
| Ortholog in Animals | Alpaca_ PIK3C2G ( ortholog_one2one ) Dog_ PIK3C2G ( ortholog_one2one ) Macaque_ PIK3C2G ( ortholog_one2one ) Mouse_ Pik3c2g ( ortholog_one2one ) Pig_ PIK3C2G ( ortholog_one2one ) Rat_ Pik3c2g ( ortholog_one2one ) Rabbit_ PIK3C2G ( ortholog_one2one ) |
| Ohnologs | PIK3C2A, PIK3C2B |
| Paralogs | PIK3CG, PIK3CB, PIK3C2B, PIK3C2A, PI4KB, PIK3CA, PI4KA, PIK3C3, PIK3CD |
| Tissue | stomach, epididymis, parotid.gland, seminal.vesicle, vas.deferens |
| Tissue Specificity | Highly expressed in liver, prostate and testis. Lower levels in small intestine, kidney and pancreas. {ECO:0000269|PubMed:9878262}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2WWE (X-ray 1.25A ) |
| DBSNP | rs11044004 rs7133666 rs12312266 rs12099555 rs12816860 |
| Subcellular location [CC] | Membrane {ECO:0000250|UniProtKB:O70167}; Peripheral membrane protein {ECO:0000250|UniProtKB:O70167}. |
| Mouse PG classification | NA |
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