| Gene Information | |
|---|---|
| Gene Name | PLCD3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 789 |
| Protein Names | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-3) (Phospholipase C-delta-3) (PLC-delta-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000161714 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8N3E9 |
| Gene Card | PLCD3 |
| Uniprot ID | Q8N3E9 |
| Pfam | PF00168; PF14788; PF00388; PF00387 |
| In ASD | no |
| Allosteric Prediction | no (-0.512846433) |
| Ortholog in Animals | Alpaca_ PLCD3 ( ortholog_one2one ) Dog_ PLCD3 ( ortholog_one2one ) GuineaPig_ PLCD3 ( ortholog_one2one ) Macaque_ PLCD3 ( ortholog_one2one ) Mouse_ Plcd3 ( ortholog_one2one ) Pig_ PLCD3 ( ortholog_one2one ) Rat_ Plcd3 ( ortholog_one2one ) Rabbit_ PLCD3 ( ortholog_one2one ) |
| Ohnologs | PLCD4, PLCD1 |
| Paralogs | PLCG2, PLCB3, PLCE1, PLCG1, PLCB1, PLCD4, PLCD1, PLCB2, PLCB4, PLCL2, PLCH1, PLCL1, PLCZ1, PLCH2 |
| Tissue | NA |
| Tissue Specificity | Present in corneal epithelial cells (at protein level). {ECO:0000269|PubMed:15505048}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs734921 |
| Subcellular location [CC] | Membrane; Peripheral membrane protein. Cytoplasm. Cleavage furrow {ECO:0000269|PubMed:17041247}. Note=Localizes at the cleavage furrow during cytokinesis. {ECO:0000269|PubMed:17041247}. |
| Mouse PG classification | NA |
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