| Gene Information | |
|---|---|
| Gene Name | POMT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 747 |
| Protein Names | Protein O-mannosyl-transferase 1 (EC 2.4.1.109) (Dolichyl-phosphate-mannose--protein mannosyltransferase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000130714 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9Y6A1 |
| Gene Card | POMT1 |
| Uniprot ID | Q9Y6A1 |
| Pfam | PF02815; PF02366; PF16192 |
| In ASD | no |
| Allosteric Prediction | no (-1.369081156) |
| Ortholog in Animals | Alpaca_ POMT1 ( ortholog_one2one ) Dog_ POMT1 ( ortholog_one2one ) GuineaPig_ POMT1 ( ortholog_one2one ) Macaque_ POMT1 ( ortholog_one2one ) Mouse_ Pomt1 ( ortholog_one2one ) Pig_ POMT1 ( ortholog_one2one ) Rat_ Pomt1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | POMT2, SDF2, SDF2L1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs119462983 rs28941782 rs1289335417 rs1554772469 rs587777820 rs119462982 rs2296949 rs386738991 rs201073763 rs4740164 rs11243406 rs117985576 rs150367385 rs119462984 rs119462986 rs119462987 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:14699049}; Multi-pass membrane protein {ECO:0000269|PubMed:14699049}. |
| Mouse PG classification | LPG |
| click here to return to the previous page | |