Gene Information
Gene NamePOM121
OrganismHomo sapiens (Human)
Gene Length1249
Protein NamesNuclear envelope pore membrane protein POM 121 (Nuclear envelope pore membrane protein POM 121A) (Nucleoporin Nup121) (Pore membrane protein of 121 kDa)
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000196313 )
Evolutionary StageVertebrata
AlphaFoldDBQ96HA1
Gene CardPOM121
Uniprot IDQ96HA1
PfamNA
In ASDno
Allosteric Predictionyes (0.259555967)
Ortholog in AnimalsMouse_ Pom121 ( ortholog_one2many )
Rat_ Pom121 ( ortholog_one2many )
OhnologsNA
ParalogsPOM121C, POM121L2, NPAP1, POM121L12, NUP214, NUP153
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5T6W  (X-ray  1.90A 
DBSNP rs3177261 
Subcellular location [CC]Nucleus, nuclear pore complex {ECO:0000269|PubMed:17900573}. Nucleus membrane {ECO:0000269|PubMed:17900573};
Single-pass membrane protein {ECO:0000269|PubMed:17900573}. Endoplasmic reticulum membrane {ECO:0000250};
Single-pass membrane protein {ECO:0000250}. Note=Stably associated with the NPC throughout interphase and the endoplasmic reticulum during metaphase. {ECO:0000250}.
Mouse PG classificationNA
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