| Gene Information | |
|---|---|
| Gene Name | RALGPS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 583 |
| Protein Names | Ras-specific guanine nucleotide-releasing factor RalGPS2 (Ral GEF with PH domain and SH3-binding motif 2) (RalA exchange factor RalGPS2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000116191 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86X27 |
| Gene Card | RALGPS2 |
| Uniprot ID | Q86X27 |
| Pfam | PF00169; PF00617 |
| In ASD | no |
| Allosteric Prediction | no (-0.460794472) |
| Ortholog in Animals | Alpaca_ RALGPS2 ( ortholog_one2one ) Dog_ RALGPS2 ( ortholog_one2one ) GuineaPig_ RALGPS2 ( ortholog_one2one ) Macaque_ RALGPS2 ( ortholog_one2one ) Mouse_ Ralgps2 ( ortholog_one2one ) Pig_ RALGPS2 ( ortholog_one2one ) Rat_ Ralgps2 ( ortholog_one2one ) Rabbit_ RALGPS2 ( ortholog_one2one ) |
| Ohnologs | RALGPS1 |
| Paralogs | RALGPS1, RALGDS, RASGEF1A, RASGRF2, RASGRP3, SOS2, RAPGEF3, RAPGEF6, RASGRF1, RAPGEF2, RGL1, RAPGEF1, RASGEF1B, RASGRP2, RGL2, SOS1, RGL3, RAPGEF4, RGL4, RASGRP4, RAPGEFL1, RAPGEF5, RASGRP1, RASGEF1C |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35161510 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Associates with membranes through the PH domain. {ECO:0000250}. |
| Mouse PG classification | NA |
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