| Gene Information | |
|---|---|
| Gene Name | POLR3G |
| Organism | Homo sapiens (Human) |
| Gene Length | 223 |
| Protein Names | DNA-directed RNA polymerase III subunit RPC7 (RNA polymerase III subunit C7) (DNA-directed RNA polymerase III subunit G) (RNA polymerase III 32 kDa apha subunit) (RPC32-alpha) (RNA polymerase III 32 kDa subunit) (RPC32) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 12 ( ENSG00000113356 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O15318 |
| Gene Card | POLR3G |
| Uniprot ID | O15318 |
| Pfam | PF11705 |
| In ASD | no |
| Allosteric Prediction | no (-0.80004588) |
| Ortholog in Animals | Alpaca_ POLR3G ( ortholog_one2one ) Macaque_ POLR3G ( ortholog_one2one ) |
| Ohnologs | POLR3GL |
| Paralogs | NA |
| Tissue | substantia.nigra |
| Tissue Specificity | Barely detectable in differentiated tissues. Expressed in embryonic stem cells and in other dividing cells, such as some tumor cell lines. {ECO:0000269|PubMed:20154270, ECO:0000269|PubMed:24107381, ECO:0000269|PubMed:28494942}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7A6H (EM 3.30A ) 7AE1 (EM 2.80A ) 7AE3 (EM 3.10A ) 7AEA (EM 3.40A ) 7D58 (EM 2.90A ) 7D59 (EM 3.10A ) 7DN3 (EM 3.50A ) 7DU2 (EM 3.35A ) 7FJI (EM 3.60A ) 7FJJ (EM 3.60A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:20154270, ECO:0000269|PubMed:21898682}. Cytoplasm {ECO:0000250|UniProtKB:Q6NXY9}. Note=Excluded from nucleoli (PubMed:21898682). In zygotes and the 2-cell stage embryos, mainly in the cytoplasm. Starts to localize to the nucleus in the 8-16 cell stage embryo and early blastocysts (By similarity). {ECO:0000250|UniProtKB:Q6NXY9, ECO:0000269|PubMed:21898682}. |
| Mouse PG classification | NA |
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