| Gene Information | |
|---|---|
| Gene Name | PYGL |
| Organism | Homo sapiens (Human) |
| Gene Length | 847 |
| Protein Names | Glycogen phosphorylase, liver form (EC 2.4.1.1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000100504 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P06737 |
| Gene Card | PYGL |
| Uniprot ID | P06737 |
| Pfam | PF00343 |
| In ASD | yes |
| Allosteric Prediction | yes (1.088951906) |
| Ortholog in Animals | Alpaca_ PYGL ( ortholog_one2one ) Dog_ PYGL ( ortholog_one2one ) GuineaPig_ PYGL ( ortholog_one2one ) Macaque_ PYGL ( ortholog_one2one ) Mouse_ Pygl ( ortholog_one2one ) Pig_ PYGL ( ortholog_one2one ) Rat_ Pygl ( ortholog_one2one ) Rabbit_ PYGL ( ortholog_one2one ) |
| Ohnologs | PYGB, PYGM |
| Paralogs | PYGB, PYGM |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.002240(Rat);0.022222(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1EM6 (X-ray 2.20A ) 1EXV (X-ray 2.40A ) 1FA9 (X-ray 2.40A ) 1FC0 (X-ray 2.40A ) 1L5Q (X-ray 2.25A ) 1L5R (X-ray 2.10A ) 1L5S (X-ray 2.10A ) 1L7X (X-ray 2.30A ) 1XOI (X-ray 2.10A ) 2ATI (X-ray 1.90A ) 2QLL (X-ray 2.56A ) 2ZB2 (X-ray 2.45A ) 3CEH (X-ray 2.80A ) 3CEJ (X-ray 3.30A ) 3CEM (X-ray 2.47A ) 3DD1 (X-ray 2.57A ) 3DDS (X-ray 1.80A ) 3DDW (X-ray 1.90A ) |
| DBSNP | rs946616 rs1042195 rs113993976 rs113993977 rs2228499 rs35831273 rs1042210 rs34313873 rs78558135 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000305|PubMed:22225877}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |