| Gene Information | |
|---|---|
| Gene Name | POLR2J |
| Organism | Homo sapiens (Human) |
| Gene Length | 117 |
| Protein Names | DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a) (RPB11a) (DNA-directed RNA polymerase II subunit J-1) (RNA polymerase II 13.3 kDa subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000005075 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P52435 |
| Gene Card | POLR2J |
| Uniprot ID | P52435 |
| Pfam | PF13656 |
| In ASD | no |
| Allosteric Prediction | no (-0.789304775) |
| Ortholog in Animals | Dog_ POLR2J ( ortholog_one2many ) Mouse_ Polr2j ( ortholog_one2many ) Rat_ Polr2j ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | POLR1D, POLR2J2, POLR2J3 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. High expression was found in heart and skeletal muscle. {ECO:0000269|PubMed:11747469}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.599169(Rat);0.255803(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5IY6 (EM 7.20A ) 5IY7 (EM 8.60A ) 5IY8 (EM 7.90A ) 5IY9 (EM 6.30A ) 5IYA (EM 5.40A ) 5IYB (EM 3.90A ) 5IYC (EM 3.90A ) 5IYD (EM 3.90A ) 6DRD (EM 3.90A ) 6O9L (EM 7.20A ) 6XRE (EM 4.60A ) 7LBM (EM 4.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:9852112}. |
| Mouse PG classification | NA |
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