| Gene Information | |
|---|---|
| Gene Name | POLR1F |
| Organism | Homo sapiens (Human) |
| Gene Length | 338 |
| Protein Names | DNA-directed RNA polymerase I subunit RPA43 (DNA-directed RNA polymerase I subunit F) (Twist neighbor protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000105849 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q3B726 |
| Gene Card | POLR1F |
| Uniprot ID | Q3B726 |
| Pfam | PF17875 |
| In ASD | no |
| Allosteric Prediction | no (-0.77367515) |
| Ortholog in Animals | Alpaca_ POLR1F ( ortholog_one2one ) Dog_ POLR1F ( ortholog_one2one ) GuineaPig_ POLR1F ( ortholog_one2one ) Macaque_ POLR1F ( ortholog_one2one ) Mouse_ Polr1f ( ortholog_one2one ) Pig_ POLR1F ( ortholog_one2one ) Rat_ Polr1f ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | POLR3H, POLR2G |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in all fetal and adult tissues tested, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues. {ECO:0000269|PubMed:12438708}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.093367(Rat);0.079035(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7OB9 (EM 2.70A ) 7OBA (EM 3.10A ) 7OBB (EM 3.30A ) 7VBA (EM 2.89A ) 7VBB (EM 2.81A ) 7VBC (EM 3.01A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000250}. |
| Mouse PG classification | NA |
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