| Gene Information | |
|---|---|
| Gene Name | POLR1A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1720 |
| Protein Names | DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000068654 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O95602 |
| Gene Card | POLR1A |
| Uniprot ID | O95602 |
| Pfam | PF04997; PF00623; PF04983; PF05000; PF04998 |
| In ASD | no |
| Allosteric Prediction | yes (0.162568864) |
| Ortholog in Animals | Alpaca_ POLR1A ( ortholog_one2one ) Dog_ POLR1A ( ortholog_one2one ) GuineaPig_ POLR1A ( ortholog_one2one ) Macaque_ POLR1A ( ortholog_one2one ) Mouse_ Polr1a ( ortholog_one2one ) Pig_ POLR1A ( ortholog_one2one ) Rat_ Polr1a ( ortholog_one2one ) Rabbit_ POLR1A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | POLR3A, POLR2A |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.089017(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7OB9 (EM 2.70A ) 7OBA (EM 3.10A ) 7OBB (EM 3.30A ) 7VBA (EM 2.89A ) 7VBB (EM 2.81A ) 7VBC (EM 3.01A ) 8A43 (EM 4.09A ) |
| DBSNP | rs4832242 rs17026866 rs35239368 rs35443467 rs794729674 rs34302587 rs34892520 rs751377255 rs35093541 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000250|UniProtKB:P10964}. Chromosome {ECO:0000250|UniProtKB:O35134}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |