| Gene Information | |
|---|---|
| Gene Name | POLN |
| Organism | Homo sapiens (Human) |
| Gene Length | 900 |
| Protein Names | DNA polymerase nu (EC 2.7.7.7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000130997 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q7Z5Q5 |
| Gene Card | POLN |
| Uniprot ID | Q7Z5Q5 |
| Pfam | PF00476; PF18049 |
| In ASD | no |
| Allosteric Prediction | no (-0.896717731) |
| Ortholog in Animals | Alpaca_ POLN ( ortholog_one2one ) Dog_ POLN ( ortholog_one2one ) GuineaPig_ POLN ( ortholog_one2one ) Macaque_ POLN ( ortholog_one2one ) Mouse_ Poln ( ortholog_one2one ) Pig_ POLN ( ortholog_one2one ) Rat_ Haus3 ( ortholog_one2one ) Rabbit_ POLN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis and heart. Weakly expressed in skeletal muscle. {ECO:0000269|PubMed:12794064}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4XVI (X-ray 3.10A ) 4XVK (X-ray 2.95A ) 4XVL (X-ray 3.30A ) 4XVM (X-ray 3.20A ) |
| DBSNP | rs2353552 rs35884361 rs10018786 rs11725880 rs10011549 rs9328764 rs34574483 rs34554757 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12794064}. |
| Mouse PG classification | NA |
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