Gene Information
Gene NameMIS12
OrganismHomo sapiens (Human)
Gene Length205
Protein NamesProtein MIS12 homolog
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000167842 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9H081
Gene CardMIS12
Uniprot IDQ9H081
PfamPF05859
In ASDno
Allosteric Predictionno (-0.70217695)
Ortholog in AnimalsAlpaca_ MIS12 ( ortholog_one2one )
Dog_ MIS12 ( ortholog_one2many )
Macaque_ MIS12 ( ortholog_one2one )
Mouse_ Mis12 ( ortholog_one2one )
Pig_ MIS12 ( ortholog_one2one )
Rat_ Mis12 ( ortholog_one2one )
Rabbit_ MIS12 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.086583(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5LSJ  (X-ray  3.25A  5LSK  (X-ray  3.50A 
DBSNP rs16954781 
Subcellular location [CC]Chromosome, centromere, kinetochore {ECO:0000269|PubMed:12515822, ECO:0000269|PubMed:15502821}. Note=Associated with the kinetochore. {ECO:0000269|PubMed:12515822, ECO:0000269|PubMed:15502821}.
Mouse PG classificationNA
click here to return to the previous page