Gene Information
Gene NamePOLE4
OrganismHomo sapiens (Human)
Gene Length117
Protein NamesDNA polymerase epsilon subunit 4 (DNA polymerase II subunit 4) (DNA polymerase epsilon subunit p12)
Target Namedna polymerase epsilon subunit 4
Target TypeNA
Gene Age544 ( ENSG00000115350 )
Evolutionary StageEukaryota
AlphaFoldDBQ9NR33
Gene CardPOLE4
Uniprot IDQ9NR33
PfamPF00808
In ASDno
Allosteric Predictionno (-0.36609896)
Ortholog in AnimalsAlpaca_ POLE4 ( ortholog_one2one )
Dog_ POLE4 ( ortholog_one2one )
GuineaPig_ POLE4 ( ortholog_one2one )
Macaque_ POLE4 ( ortholog_one2one )
Mouse_ Pole4 ( ortholog_one2one )
Pig_ POLE4 ( ortholog_one2one )
Rat_ Pole4 ( ortholog_one2one )
OhnologsNA
ParalogsDRAP1, NFYC
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.004740(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs12366 
Subcellular location [CC]Nucleus {ECO:0000305}.
Mouse PG classificationNA
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