| Gene Information | |
|---|---|
| Gene Name | POLE3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 147 |
| Protein Names | DNA polymerase epsilon subunit 3 (Arsenic-transactivated protein) (AsTP) (Chromatin accessibility complex 17 kDa protein) (CHRAC-17) (HuCHRAC17) (DNA polymerase II subunit 3) (DNA polymerase epsilon subunit p17) |
| Target Name | dna polymerase epsilon subunit 3 |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000148229 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NRF9 |
| Gene Card | POLE3 |
| Uniprot ID | Q9NRF9 |
| Pfam | PF00808 |
| In ASD | no |
| Allosteric Prediction | no (-0.573741071) |
| Ortholog in Animals | Alpaca_ POLE3 ( ortholog_one2one ) Dog_ POLE3 ( ortholog_one2one ) GuineaPig_ POLE3 ( ortholog_one2one ) Macaque_ POLE3 ( ortholog_one2one ) Mouse_ Pole3 ( ortholog_one2one ) Pig_ POLE3 ( ortholog_one2one ) Rat_ AABR07027368.1 ( ortholog_one2one ) Rabbit_ POLE3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10880450}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002528(Rat);0.074074(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs36023979 rs34852828 rs35933626 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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