| Gene Information | |
|---|---|
| Gene Name | CYBA |
| Organism | Homo sapiens (Human) |
| Gene Length | 195 |
| Protein Names | Cytochrome b-245 light chain (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Neutrophil cytochrome b 22 kDa polypeptide) (Superoxide-generating NADPH oxidase light chain subunit) (p22 phagocyte B-cytochrome) (p22-phox) (p22phox) |
| Target Name | nadph oxidase |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000051523 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P13498 |
| Gene Card | CYBA |
| Uniprot ID | P13498 |
| Pfam | PF05038 |
| In ASD | no |
| Allosteric Prediction | yes (0.406044935) |
| Ortholog in Animals | Alpaca_ CYBA ( ortholog_one2one ) Dog_ CYBA ( ortholog_one2one ) GuineaPig_ CYBA ( ortholog_one2one ) Macaque_ CYBA ( ortholog_one2one ) Mouse_ Cyba ( ortholog_one2one ) Pig_ CYBA ( ortholog_one2one ) Rat_ Cyba ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WLP (NMR - ) 7YXW (X-ray 2.50A ) |
| DBSNP | rs28941476 rs179363891 rs179363891 rs179363890 rs179363893 rs4673 rs104894513 rs179363892 rs104894510 rs104894514 rs179363894 rs119103269 rs104894515 rs72667005 rs1049254 rs72667006 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:15585859, ECO:0000269|PubMed:22808130}. Note=As unassembled monomer may localize to the endoplasmic reticulum. {ECO:0000250|UniProtKB:Q61462}. |
| Mouse PG classification | LPG |
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