Gene Information
Gene NameSEMA6D
OrganismHomo sapiens (Human)
Gene Length1073
Protein NamesSemaphorin-6D
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000137872 )
Evolutionary StageEumetazoa
AlphaFoldDBQ8NFY4
Gene CardSEMA6D
Uniprot IDQ8NFY4
PfamPF01437; PF01403
In ASDno
Allosteric Predictionno (-1.077065266)
Ortholog in AnimalsAlpaca_ SEMA6D ( ortholog_one2one )
Dog_ SEMA6D ( ortholog_one2one )
GuineaPig_ SEMA6D ( ortholog_one2one )
Macaque_ SEMA6D ( ortholog_one2one )
Mouse_ Sema6d ( ortholog_one2one )
Pig_ SEMA6D ( ortholog_one2one )
Rat_ Sema6d ( ortholog_one2one )
Rabbit_ SEMA6D ( ortholog_one2one )
OhnologsSEMA6B, SEMA6A, SEMA6C, SEMA4D, SEMA4A
ParalogsSEMA4D, SEMA3A, SEMA3F, SEMA6C, SEMA3E, SEMA3D, SEMA6B, SEMA4B, SEMA4F, SEMA3B, SEMA4G, SEMA3C, SEMA5A, SEMA4A, SEMA5B, SEMA7A, SEMA3G, SEMA4C, SEMA6A
Tissuepineal.gland, placenta
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3743279  rs532598  rs16960074 
Subcellular location [CC][Isoform 1]: Cell membrane;
Single-pass type I membrane protein.;
[Isoform 2]: Cell membrane;
Single-pass type I membrane protein.;
[Isoform 3]: Cell membrane;
Single-pass type I membrane protein.;
[Isoform 4]: Cell membrane;
Single-pass type I membrane protein.;
[Isoform 5]: Cell membrane;
Single-pass type I membrane protein.;
[Isoform 7]: Cytoplasm.
Mouse PG classificationNA
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