| Gene Information | |
|---|---|
| Gene Name | POGZ |
| Organism | Homo sapiens (Human) |
| Gene Length | 1410 |
| Protein Names | Pogo transposable element with ZNF domain (Suppressor of hairy wing homolog 5) (Zinc finger protein 280E) (Zinc finger protein 635) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000143442 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q7Z3K3 |
| Gene Card | POGZ |
| Uniprot ID | Q7Z3K3 |
| Pfam | PF03184; PF03221 |
| In ASD | no |
| Allosteric Prediction | no (-1.045705001) |
| Ortholog in Animals | Alpaca_ POGZ ( ortholog_one2one ) Dog_ POGZ ( ortholog_one2one ) GuineaPig_ POGZ ( ortholog_one2one ) Macaque_ POGZ ( ortholog_one2one ) Mouse_ Pogz ( ortholog_one2one ) Pig_ POGZ ( ortholog_one2one ) Rat_ Pogz ( ortholog_one2one ) Rabbit_ POGZ ( ortholog_one2one ) |
| Ohnologs | ZNF280D |
| Paralogs | TIGD6, TIGD7, TIGD4, TIGD2, TIGD3, TIGD1, POGK, JRKL, TIGD5, CENPB, JRK |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.0875(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2E72 (NMR - ) 2N3A (NMR - ) 6EMP (NMR - ) |
| DBSNP | rs35198305 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:26721387}. Chromosome. Cytoplasm. Note=According to some authors, it is not localized to mitotic chromatin (PubMed:19244240). Recruited to trimethylated 'Lys-9' of histone H3 (H3K9me3). {ECO:0000269|PubMed:19244240}. |
| Mouse PG classification | NA |
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